IndraLab

Statements


CYLD translocates to the centrosome. 2 / 2
| 2

reach
"Mechanistically, Spata2 recruits the deubiquitinase CYLD to the centrosome for deubiquitination of polo like kinase 4 (PLK4), the master regulator of centrosome duplication."

reach
"Firstly, the DUB CYLD is recruited to centrosomes and the basal body of cilia via its interaction with CAP350 (centrosome associated protein of 350kDa), where it has to be present and catalytically active to promote docking of basal bodies at the plasma membrane and hence ciliogenesis [XREF_BIBR]."