IndraLab

Statements

IFNL4 increases the amount of USP18. 3 / 3
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"We suspect that whereas increased TNF-alpha does contribute to USP18 expression, there are other stimuli, for example, LPS and perhaps the recently described interferon-lambda 4, that also modulate hepatic USP18 expression."
27009955
reach
"In hepatoma cells, IFNL4 gene transfection or recombinant IFN-lambda4 protein treatment robustly increased the protein levels of ISG15 and USP18 in an IFNLR1 dependent manner and potently blocked IFN-alpha signalling."
28630501
reach
"We suspect that whereas increased TNF-α does contribute to USP18 expression, there are other stimuli, for example, LPS and perhaps the recently described interferon-lambda 4 (56), that also modulate hepatic USP18 expression."
27009955