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USP1 activates monoubiquitinated PCNA accumulation ssDNA gaps cells treated HU doses. 1 / 1
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eidos
"Loss of USP1 , which is required to remove ubiquitin from monoubiquitinated PCNA ( Huang et al ., 2006 ) leads to increased levels of monoubiquitinated PCNA and accumulation of ssDNA gaps in BRCA1-deficient cells treated with low HU doses ( Lim et al ., 2018 ) ."