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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP7 activates reactive oxygen species. 4 / 4

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"Flow cytometry results showed that USP7 overexpression induced pyroptosis and ROS production which was blocked by apocynin (XREF_FIG)."

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"ROS assay showed that H 2 O 2 elevated ROS production which was abolished by USP7 KD or USP7 inhibition (XREF_FIG)."

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"These data suggest that H2O2 induced ROS production , NLRP3 inflammasome activation , and pyroptosis by increasing USP7 ."

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"ROS assay showed that H2O2 elevated ROS production which was abolished by USP7 KD or USP7 inhibition ( Figure 2B ) ."

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USP7 activates reactive oxygen species. 4 / 4

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