IndraLab

Statements

VAMP2 binds KCNB1. 5 / 5
| 5
sparser
"It should be noted that in a different set of experiments, some VAMP2 binding to Kv2.1 C1a peptide was observed; its intensity was always significantly lower than that of syntaxin (not shown)."
18167541
sparser
"We report here that Kv2.1 interacts with VAMP2, the vesicular SNARE partner that is also present at high concentration in neuronal plasma membrane."
18542995
sparser
"Given the proposed role for surface VAMP2 in the regulation of the vesicle cycle and the important role for the sustained Kv2.1 current in the regulation of dendritic calcium entry during high-frequency stimulation, the interaction of VAMP2 with Kv2.1 N terminus may contribute, alongside with the interaction of syntaxin with Kv2.1 C terminus, to the activity dependence of DCV release."
18542995
sparser
"Recently, we showed that also VAMP2, the vesicular SNARE, interacts physically and functionally with Kv2.1."
18636750
sparser
"Using the interaction of VAMP2 with Kv2.1 in Xenopus oocytes as a probe, we showed that coexpression of the t-SNARE complex with VAMP2 abolished the VAMP2 effect on channel inactivation and reduced the amount of VAMP2 that coprecipitated with Kv2.1."
18636750