IndraLab

Statements

JAK2 phosphorylates JAK2 on Y1008. 9 / 9
3 2 1 | 2 1
rlimsp
"Autophosphorylation of Jak2 kinase at Tyr1007/1008 sites also was strongly inhibited in the range of 15 μM of BBMD3 in human melanoma cells at 4h after treatment."
22717603
phosphoelm
No evidence text available
11818507
biopax:netpath
No evidence text available
18718905
biopax:netpath
No evidence text available
17565041
biopax:netpath
No evidence text available
11585385
reach
"JAK2 and STAT1 signaling was activated by IFNgamma, resulting in phosphorylation of JAK2 (Tyr 1007/1008), and STAT1 (Tyr 701) at 1h and 6h, whereas IL-1beta had no effect."
33731692
hprd
No evidence text available
9111318
hprd
No evidence text available
11818507
reach
"65 JAK2 dimerization induces the trans‐phosphorylation of each JAK2 protein at Y1007 and Y1008 in the activation loop of the tyrosine kinase (TK) domain leading to TK activation."
36916035