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Gram increases the amount of CYLD. 2 / 2
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"Such a function of CYLD was suggested by the finding that the expression of CYLD is induced by proinflammatory cytokines, TNF-alpha and IL-1beta, and the Gram negative bacterium Haemophilus influenzae."

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"Indeed, both TNF-alpha and non typeable Haemophilus influenzae (NTHi), a common Gram negative bacterial pathogen that causes respiratory infections, can upregulate CYLD expression, suggesting that CYL[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"