IndraLab

Statements


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reach
"HuR may modulate translation of several ARE-mRNAs by a process that is independent of ARE or 3 ' UTR, which involves binding of HuR to IRES in the 5 ' UTR.19, 20, 21 AREs mediate their effects on mRNA decay by first enhancing deadenylation (polyA shortening), a first step in mRNA decay facilitated by CCR4 and NOT and PAN2 and PAN complexes."