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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OTUD1 activates protein. 1 / 1

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eidos

"OTUD1 interacts with Smurf1 and functions as a deubiquitinase to remove the K48-linked ubiquitination of Smurf1 , prevent its self-ubiquitination degradation , and upregulate its protein level ; whereas the binding of Ndfip1 to MAVS recruits Smurf1 to MAVS , and the interaction between Ndfip1 and Smurf1 enhances the self-ubiquitination ( possibly k63-linked ) and enzyme activity of Smurf1 ( Table 1 ) ( 47 , 49 ) ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...