IndraLab

Statements

CYLD deubiquitinates MIB2. 3 / 3
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reach
"Moreover, MIB2, an E3 ligase for the Notch ligand JAG2, is deubiquitinated and stabilized by CYLD."
27844253
reach
"As we demonstrated that MIB2 can ubiquitylate itself as well as CYLD, we postulated that CYLD, as an ubiquitin hydrolase, might deubiquitylate MIB2, hence providing a potential mechanism of mutual regulation."
25565632
ubibrowser
"To dissect <span class="match term0">CYLD</span> function we used a proteomics approach to identify <span class="match term0">CYLD</span> interacting proteins and identified <span class="match term1">MIB2</span>, an ubiquitin ligase enzyme involved in Notch signalling, as a protein which interacts with <span class="match term0">CYLD</span>"
25565632