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Casp14 activates USP45. 1 / 1
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"In agreement with these clinical findings, the LL-IL35-treated mice had markedly reduced Ly-6G + CD11b + cells (neutrophils) infiltrating the joints (Figure 2A ) representing a 7-and 5-fold reduction compared to The synthetic insert encodes in order: the usp45 secretion peptide genetically fused in-frame to the p35 subunit, a short flexible linker, fused to the EBI3."