IndraLab

Statements


USP8 deubiquitinates STAM. 3 / 4
1 | 3

reach
"In addition, we identified STAM and NFX1, which are known to be deubiquitylated by USP8 and USP9 respectively."

reach
"USP8 deubiquitinates STAM, preventing its degradation by the proteasome [XREF_BIBR], and Nrdp1, an E3 required for the lysosomal degradation of EGFR family members ErbB3 and ErbB4 [XREF_BIBR]."

reach
"USP8 modulates EGFR trafficking by regulating STAM de-ubiquitination on early endosomes 11."