IndraLab

Statements


MARCHF8 activates USP35. 4 / 4
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"In the present study, we first identified USP35, a member of the USP superfamily, can be up-regulated by the miR let-7a."

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"USP35 activated by miR let-7a inhibits cell proliferation and NF-kappaB activation through stabilization of ABIN-2."

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"These findings indicate that USP35 up-regulated by miR let-7a potentially functions as a tumor suppressor and inhibits tumor growth."

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"The molecular pathways by which miR let-7a up-regulates USP35 need to be further investigated."