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USP14 inhibits H R-induced USP14 p-p65 proinflammatory cytokines potential USP14 preeclampsia. 1 / 1
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"H / R , hypoxia / reoxygenation ; mRNA , messenger RNA ; NF-kappaB , nuclear factor kappa B ; RT-qPCR , quantitative reverse transcription PCR ; TNF-alpha , tumor necrosis factor-alpha ; USP14 , Ubiquitin-specific proteases 14 Depletion of USP14 abrogated H / R-induced upregulation of USP14 , p-p65 , and proinflammatory cytokines To further study the potential role of USP14 in preeclampsia , we aimed to knockdown of USP14 in trophoblast cell lines ."