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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Dioxygen leads to the methylation of CDKN2A. 3 / 3

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"Of interest, high PlGF expressing tumors such as choriocarcinoma also have hypermethylation of p16ink4a, which may be mediated by the reactive oxygen species mediated pathway for regulation of PlGF expression."

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"Reactive oxygen induced carcinogenesis causes hypermethylation of p16 (Ink4a) and activation of MAP kinase."

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"Our conclusions from this is that reactive oxygen induced carcinogens cause hypermethylation of p16ink4a and MAP kinase activation."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

Dioxygen leads to the methylation of CDKN2A. 3 / 3

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