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Doxycycline decreases the amount of USP7. 2 / 2
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"The addition of doxycycline to the culture medium reduced USP7 expression as measured at both the mRNA and protein levels, and as expected, USP7 silencing stabilized p53, resulting in induction of its[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Addition of doxycycline to the culture medium reduced USP7 expression as measured at both mRNA (XREF_SUPPLEMENTARY) and protein (XREF_FIG) levels, and as expected, USP7 silencing stabilized p53, resulting in induction of its target genes (XREF_FIG; XREF_SUPPLEMENTARY)."