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Doxycycline decreases the amount of USP7. 1 / 1
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"Addition of doxycycline to the culture medium reduced USP7 expression as measured at both mRNA (XREF_SUPPLEMENTARY) and protein (XREF_FIG) levels, and as expected, USP7 silencing stabilized p53, resulting in induction of its target genes (XREF_FIG; XREF_SUPPLEMENTARY)."