IndraLab

Statements

USP1 activates Osteosarcoma. 5 / 6
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"Moreover, inhibition of USP1 expression suppresses tumor growth in osteosarcoma (98)."
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"The silencing or inhibition of USP1 expression inhibits cell proliferation in osteosarcoma, prostate cancer, and ovarian cancer [22,23,24], but USP1 does not affect the proliferation of tumor cells in liver, gastric, or breast cancers [25,26], indicating that its role differs in various tumors."
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"Furthermore, Yuan et al. [24] also reported that osteosarcoma progression is suppressed by USP1 inhibition via destabilization of TAZ."
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"USP1 knockdown similarly reduced proliferation in HOS, SAOS, and SJSA, but not MG-63 osteosarcoma cells."
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"USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ."
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