IndraLab

Statements

ANTXR1 binds IL1B and IL-1α. 5 / 5
| 5
sparser
"IL-1α and IL-1β bind to the IL-1 receptor 1 (IL-1R1) [ xref , xref ]."
28793896
sparser
"IL-1α and IL-1β both bind to the IL-1 receptor 1 (IL-1RI), which is present on almost all cell types, including structural cells such as airway epithelial cells [ xref , xref ]."
22403589
sparser
"Both IL-1α and IL-1β bind to IL-1 receptor 1 (IL-1R1)."
27313051
sparser
"IL-1 signaling is activated when either of the agonistic IL-1 ligands i.e. IL-1α or IL-1β binds to the IL-1 receptor 1 (IL-1R1) which then forms a complex with the IL-1 receptor accessory protein (IL-1RAcP)."
27738319
sparser
"Both IL-1α and IL-1β interact with the IL-1 receptor 1 (IL-1R1) and recruit the IL-1 receptor accessory protein (IL-1R3, formerly IL-1RAcP) to induce a downstream signal via several inflammatory kinases, such as Myd88, ERK, JNK and NFκB, leading to transcription of inflammatory, catabolic genes [ xref - xref ]."
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