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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CDK5 phosphorylates ASXL1. 2 / 2

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"Regarding the inhibitory role of Cdk5 at synapses, Cdk5-dependent phosphorylation of the Rho guanine nucleotide exchange factor ephexin1 or the Wiskott–Aldrich syndrome protein family verprolin homologous protein 1 (WAVE1) reduces the number of dendritic spines through the modulation of actin dynamics xref xref ."

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"CDK5 phosphorylates Wiskott-Aldrich syndrome protein-family verprolin homologous protein 1 (WAVE-1) to inhibit actin polymerisation [ xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...