IndraLab

Statements


CYLD inhibits initiation necroptosis. 2 / 2
| 2

eidos
"FLIPL and caspase-8 form a heterodimer to cleave RIPK1 , RIPK3 and CYLD , which inhibit the initiation of necroptosis ."

eidos
"In general , when the activity of caspase-8 is present , FLIPL and caspase-8 combine with each other to form a heterodimer to cleave RIPK1 , RIPK3 and CYLD , which prevents the initiation of necroptosis ( 51 ) ."