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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Catalytically active GFRA1 activates MET. 1 / 1

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"Both branching and chemotaxis are promoted by GDNF in cells co-expressing RET and GFR1, which mimics the effects of hepatocyte growth factor (HGF) signalling through the Met receptor tyrosine kinase in wild-type MDCK cells. GDNF induces Met phosphorylation in several RET-deficient but GFR1-positive cells, as well as in cell lines coexpressing GFR1 and RET. Met might therefore contribute to RET-independent GDNF signalling."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...