IndraLab
Statements
reach
"Thiolutin also inhibits the JAMM metalloproteases Csn5, the deneddylase of the COP9 signalosome; AMSH, which regulates ubiquitin dependent sorting of cell-surface receptors; and BRCC36, a K63 specific deubiquitinase of the BRCC36 containing isopeptidase complex and the BRCA1, BRCA2, and containing complex."