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Interleukin activates USP17L2. 2 / 2
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"Curiously, the DUB3 gene, a part of the highly polymorphic RS447 megasatellite sequence, is induced by cytokines interleukin (IL-) 4 and IL-6 in certain mammalian cells XREF_BIBR XREF_BIBR."

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"In addition, human DUB enzyme DUB-3, highly homologous to USP17 and induced by cytokines interleukin (IL) -4 and IL-6, has been recently isolated and showed that it has significant homology to the known murine DUB subfamily members."