IndraLab

Statements

Serotonin inhibits ITCH. 7 / 7
| 7
reach
"Similar to dermatitis models, blocking serotonin signaling and PAR2 can also effectively reduce itch in dry skin models [XREF_BIBR, XREF_BIBR]."
26385480
reach
"Depletion of supraspinal serotonin reduced itch behavior, indicating that serotonergic pathways descending from the rostral ventromedial medulla may tonically facilitate itch [XREF_BIBR] (XREF_FIG)."
27578065
reach
"Therefore, we investigated if sumatriptan has inhibitory effects on serotonin induced itch in mice."
29352328
reach
"Separately, it has been shown that administration of a nitric oxide (NO) donor to skin enhances substance P induced itch in mice, while serotonin induced itch was inhibited by systemic nitric oxide synthase (NOS) inhibitors."
28119997
reach
"Attenuation of serotonin induced itch by sumatriptan : possible involvement of endogenous opioids."
29352328
reach
"In addition, acute itch triggered by serotonin or a selective serotonin reuptake inhibitor required both HTR7 and TRPA1."
26074006
reach
"Anecdotal and limited data suggest that gabapentin, cutaneous field stimulation, serotonin antagonists, and ultraviolet B phototherapy may attenuate itch in some of these patients."
15811075