IndraLab

Statements

USP1 inhibits response therapeutic enzalutamide. 2 / 2
| 2
eidos
"In addition , inhibition of USP1 decreased PC proliferation and promoted response to therapeutic agent enzalutamide in a KDM4A-dependent manner ."
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eidos
"The supportive evidence is as follows : ( i ) USP1 knockdown decreased PC cell proliferation in vitro and tumorigenesis in vivo , and promoted the response to therapeutic agent enzalutamide ; and ( ii ) inhibition of USP1 sensitized cancer cells to therapeutic agent enzalutamide , whereas this effect was blunted by overexpression of KDM4A ."
32133742