IndraLab

Statements


| 2

sparser
"A HOIP PUB mutant, which cannot interact with CYLD or OTULIN, activates NF-κB more prominently than HOIP wild type, confirming a critical role of CYLD and OTULIN as negative regulators."

sparser
"Our analysis of LUBAC obtained from non-stimulated cells confirmed previous reports that CYLD and OTULIN bind to the PUB domain of HOIP ( xref )."