IndraLab

Statements

JAK2 leads to the phosphorylation of JAK2 on Y1007. 2 / 11
3 2 3 1 | 2
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"65 JAK2 dimerization induces the trans‐phosphorylation of each JAK2 protein at Y1007 and Y1008 in the activation loop of the tyrosine kinase (TK) domain leading to TK activation."
36916035
reach
"JAK2 and STAT1 signaling was activated by IFNgamma, resulting in phosphorylation of JAK2 (Tyr 1007/1008), and STAT1 (Tyr 701) at 1h and 6h, whereas IL-1beta had no effect."
33731692