IndraLab
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"Moreover, coimmunoprecipitation analysis with lysates of 293H cells engineered to express FLAG-tagged RAF proteins showed that CH5126766 causes MEK1/2 to interact with all 3 FLAG-tagged RAF proteins, including FLAG-tagged BRAF V600E, whereas PD0325901 causes MEK1/2 to interact with FLAG-tagged wild-type ARAF and CRAF but not FLAG-tagged wild-type BRAF and mutant BRAF ( xref )."