IndraLab

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"A number of studies reported that targeting PSMD14 inhibits tumor growth and migration through SMAD3 accumulation or SLUG decrease in melanoma [27]."

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"The results also indicated that the PSMD14 knockdown plus IKE and AA further inhibits tumor growth compared to PSMD14 knockdown or PSMD14 knockdown plus IKE (fig."

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"Considering the high expression of PSMD14 in various cancer, efficiently inhibit PSMD14 expression might repress tumorigenesis and tumor metastasis and then improve the survival outcomes of patients, [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Consistent with these findings, IHC staining for Ki67 showed a similar trend, indicating reduced cell proliferation in the PSMD14-depleted tumors (Fig. 3G)."