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USP11 deubiquitinates PRMT1. 3 / 3
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"We also find that USP11 deubiquitylates PRMT1 and that this correlates with an increase in the methylation of the PRMT1 substrate MRE11."
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"More interestingly, we did indeed identify USP11 as a PRMT1 DUB because knockdown of USP11 increased PRMT1 ubiquitylation, whilst ectopic overexpression suppressed ubiquitylation in a USP11 catalytic-dependent manner (Fig. 7b and Supplementary Fig. 5b)."
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"USP11 deubiquitylation of PRMT1 regulates methyltransferase activity."
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