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Modified USP22 increases the amount of TGFB1. 2 / 2
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"In diabetic nephropathy, the increased expression of USP22 reduced the Sirt1 ubiquitination and degradation, and decreased fibronectin and TGF-beta1 expression in glomerular mesangial cells under both[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, we have found overexpression of USP22 correlated with high TGF-beta1 expression in the lung ADC tissues.To determine whether USP22 expression in lung ADC cells induced EMT by changing the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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