IndraLab

Statements

Antagonist inhibits ITCH. 6 / 6
| 6
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"It has been known for decades that analgesia obtained with mu opioids induces itch, most probably via reduction of inhibition of pain fibers, whereas mu antagonists, such as naltrexone, inhibit itch."
20948846
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"An intradermal injection of histamine elicits itch, which is inhibited by a histamine H 1 receptor antagonist (Hägermark et al., 1978) ."
11011046
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"Furthermore, previous studies have shown that opioid μ antagonists inhibit the substance P–induced itch in mice 25 and alleviate the itch in patients with AD and cholestatic pruritus."
24641902
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"It is well known that histamine H(1) receptor antagonists inhibit the itch and rhinorhea, but do not block the allergic nasal congestion."
12359275
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"Indeed, it has now been shown that a selective H₄R antagonist can inhibit histamine-induced itch in humans."
25861785
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"In female BalbC mice, H2R agonist (dimaprit) failed to cause scratching and H2R antagonist (cimetidine) could not inhibit histamine-induced itch in mice ( xref )."
21841076