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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified mutated GSK3B decreases the amount of IRS1. 1 / 1

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"Overexpression of the constitutively active GSK3beta mutant significantly reduced IRS1 protein levels (XREF_FIG, lane c versus lane a), whereas overexpression of the kinase deficient mutant slightly increased the level of IRS1 protein (XREF_FIG, lane b versus lane a)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...