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Statements


PSMD14 inhibits TGFBR. 2 / 2
| 2

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"In addition, while the treatment of the cells with lysosome inhibitor bafilomycin A1 (BFA1) rescued POH1 knockdown-mediated destabilization of the TGF-β receptors (Fig. 5d), the proteasome inhibitor Mg132 did not produce similar results (Fig. S4d), demonstrating the requirement of lysosomal activity in this process."

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"Accordingly, POH1 down-regulation efficiently decreased the stability of the TGF-β receptors (Fig. 4g)."