IndraLab

Statements


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"This result further verified that CDK11 p46 is responsible for the increased association of eIF3f with the eIF3 core complex."

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"The authors suggest that the cytosolic eIF3f is phosphorylated during apoptosis, which results in a stronger association of eIF3f to the eIF3 core complex leading to translation inhibition."

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"Phosphorylation by CDK11 p46 increases the association of eIF3f with the eIF3 core complex during apoptosis."

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"To further confirm that the increased association of eIF3f with the eIF3 core complex during apoptosis is related to the phosphorylation of eIF3f by CDK11 p46 , we performed a similar experiment using CDK11 p46 transfected cells."