
IndraLab
Statements
reach
"Although still a matter of debate, EGFR deubiquitination by the ESCRT-associated deubiquitinating (DUB) enzyme UBPY (ubiquitin-specific protease 8) appears to facilitate the transfer of activated EGFRs from early ubiquitin-binding ESCRT complexes (ESCRT-0, -I, -II) to ESCRT-III (Mizuno et al., 2005; Row et al., 2006; Alwan and van Leeuwen, 2007)."