IndraLab

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EGF binds EGFR and NEDD4. 2 / 2
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"Co-immunoprecipitation assay found that NEDD4 is associated with EGFR complex upon EGF stimulation, and IHC staining indicates that NEDD4 is co-expressed with EGFR in lung adenocarcinoma tumor tissues, suggesting that NEDD4 might mediate lung cancer cell migration by interaction with the EGFR signaling complex."

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"In this research article, we demonstrated that NEDD4 interacts with EGFR upon EGF stimulation in lung cancer cells."