IndraLab

Statements



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"Furthermore, the loss-of-function assays demonstrated that knockdown of EIF3H could inhibit the progression of pancreatic cancer cells by reducing proliferation capacity, promoting apoptosis, arresting cell cycle in G2 and suppressing cell migration."

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"Knockdown of the translation initiation factor EIF3H, which scored as essential in 8 BrCa, 5 PDAC, and 3 HGS-OvCa cell lines, by any of three independent shRNAs significantly reduced cell proliferation in the HGS-OvCa cell lines tested (OVCAR5, OVCAR8 and A2780) (XREF_FIG)."

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"The in vitro results indicated that silencing EIF3H in MM cells could significantly suppress cell proliferation, promote cell apoptosis and induce cell cycle arrest."

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"We observed that EIF3H overexpression in both KYSE150 and KYSE510 cells increased cell proliferation in vitro, whereas depletion of EIF3H significantly reduced cell proliferation."

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"Knockdown of EIF3H significantly inhibited the proliferation and colony formation of OS cells in vitro, and tumour growth in nude mice in vivo."

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"EIF3H depletion in ESCC cells significantly decreased the ability of cell proliferation and mobility, examined by CCK8 assay, colony formation assay and transwell assay in vitro and xenograft and tail-vein lung metastatic mouse models in vivo."