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IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

PLK4 binds TP53 and MDM2. 3 / 3
| 3
sparser
"Moreover, the ability of oxazoloisoindolinone 3a to block the intracellular p53–MDM2 interaction in HCT116 p53 +/+ cells was checked by co-IP."
sparser
"Based on the data presented here, these 6-chloroindole compounds do not target Mdm2-p53 interactions in HCT116 cells."
sparser
"Additionally, the ability of oxazoloisoindolinone 3a to block the p53-MDM2 interaction in HCT116 p53(+/+) cells was confirmed by co-immunoprecipitation."