IndraLab

Statements



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"In this study, we for the first time verified that formononetin could alleviate the DSS induced acute colitis in mice by inhibiting NLRP3 pathway."

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"Our study here characterized that inhibitors of MALT1, would be safe and potent for the treatment of DSS induced murine colitis by inhibiting NF-kappaB and NLRP3 inflammasome activation in macrophage."

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"Ginsenoside Rk3 alleviated DSS induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway."

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"In conclusion, JWSYD improved DSS induced UC in mice, probably by reducing inflammatory cytokines and inhibiting the NLRP3 inflammasome."

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"Thus, our research shows that GDF11 alleviates DSS induced colitis by inhibiting NLRP3 inflammasome activation, providing some basis for its potential use in the treatment of UC."