IndraLab

Statements

SGK3 activates SCN5A. 3 / 5
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"SCN5A currents were activated by coexpression of either wild-type SGK1 or SGK3 or the constitutively active S422DSGK1."
12650886
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"In Xenopus oocytes, the co-expression of SGK3 and SCN5A could enhance the activity of SCN5A."
36531961
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"In SGK3 and sodium chloride transport, SGK3 is involved in up-regulating the activity of ENaC, NHE3, and Nav1.5, affecting the reabsorption of sodium by kidneys and intestines, regulating the depolarization of cardiac action potential, and maintaining hydro-salinity balance and acid-base balance."
36531961