IndraLab

Statements

USP8 activates ESCRT-0. 1 / 1

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"71 In contrast to PAR2, USP8 (or AMSH) does not impact CXCR4 ubiquitination but instead modulates the ubiquitin status of ESCRT-0 that is ubiquitinated by the E3 ligase AIP4, 23 reinforcing the idea that ubiquitination of the transport machinery represents an important regulatory event in GPCR trafficking."

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INDRA sources:

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IndraLab

Statements

USP8 activates ESCRT-0. 1 / 1

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