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TP53 bound to RPA decreases the amount of TP53. 1 / 1
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"Since a basal level of p53 is required for antioxidant activities in normal cell growth, the p53 and RPA complex formation may serve to mask this p53 domain and prevent the above-basal levels of free p53 from interrupting normal cellular functions, complementing the MDM2 function of sequestering and inactivating p53."