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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified EGF leads to the phosphorylation of EIF4EBP1. 1 / 1

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reach

"Biochemical analyses confirmed that CC214-1 successfully inhibited mTORC1 dependent 4E-BP1 and S6 phosphorylation in EGFRvIII expressing GBM cells (XREF_FIG and XREF_SUPPLEMENTARY, XREF_SUPPLEMENTARY), as well as blocked EGF induced 4E-BP1 and S6 phosphorylation in GBM cells overexpressing wild type EGFR (XREF_SUPPLEMENTARY)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...