IndraLab

Statements

PSMD4 inhibits KCNH2. 2 / 2
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"For example, drugs used to treat AF, such as quinidine and sotalol, block the hERG potassium channel and increase the APD."
20670193
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"Application of AF 3013, the active metabolite of prulifloxacin, produced only minor reduction of HERG current amplitude (tail current = -40 mV), producing a maximum blockade of 12.3 +/- 3.3% at the highest concentration tested (335 microM)."
14512100