IndraLab

Statements

USP20 binds USP33. 10 / 11
2 | 4 4
biogrid
No evidence text available
23486064
reach
"In the current studies and together with our previous report [30], we have demonstrated that both VDU1 and VDU2 also bind to the beta-domain of pVHL and several naturally occurring mutations in the be[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
12056827
sparser
"Moreover, pVHL30 is also known to interact with both USP33 and USP20, two enzymes belonging to the USP protein family, whose USP7 is a further member [ xref ]."
35205757
sparser
"Two DUBs, USP33 (or VDU-1) and USP20 (or VDU-2), interact with and regulate D2 [ xref ]."
29892818
biogrid
No evidence text available
23486064
reach
"The interactions with USP20/33 are most likely direct because (1) bacterially expressed GST-USP33 and USP20 bind to in vitro translated CP110 in binding assays (XREF_SUPPLEMENTARY) and (2) Neurl4 depletion does not affect the binding between USP33 and CP110 (XREF_SUPPLEMENTARY)."
23486064
sparser
"Like VDU1, VDU2 interacts with pVHL beta-domain and these two proteins can compete with each other to bind to pVHL."
12056827
reach
"Together, our results suggest that VDU1 and VDU2 might be relevent to pVHL related tumorigenesis.In conclusion, our previously published results and current data indicate that the interaction between [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
12056827
reach
"Further investigations are warranted to probe the biochemical and biological functions of the interaction between pVHL and VDU1 and VDU2 and to dissect functional and physiological differences between[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
12056827
sparser
"In the current studies and together with our previous report [30] , we have demonstrated that both VDU1 and VDU2 also bind to the β-domain of pVHL and several naturally occurring mutations in the β-d[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
12056827