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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified TGFB1 increases the amount of SERPINE1. 3 / 3

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"Blocked expression of TGF-beta1 can upregulate the expression of MMP-2, 3, 7 and downregulate the expression of PAI-1 mRNA in MsC."

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"In the process of liver fibrogenesis, increased TGFbeta1 levels stimulate expression of PAI-1 XREF_BIBR."

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"Nevertheless, levels of TGF-beta1, which induced PAI-1 expression in PC-3 and DU-145 cells, remained distinctly lower in comparison to PrEC cells stimulated with this cytokine."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

Modified TGFB1 increases the amount of SERPINE1. 3 / 3

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