IndraLab

Statements

CPT1A binds USP50. 6 / 6
3 | 3
biogrid
No evidence text available
34976224
sparser
"Additionally, CPT1a interacted with USP50 in 293T cells transfected with flag-USP50 (Figure xref B)."
34976224
sparser
"These observations suggest that upon LPS treatment, mitochondrial STAT3 could induce CPT1a-USP50 binding by mediating USP50 expression, leading to CPT1a stabilization, an increase in FAO and higher ATP production."
34976224
biogrid
No evidence text available
34976224
biogrid
No evidence text available
34976224
sparser
"In comparison, in the LPS-treatedRosa26 LSL-MLS-mSTAT3 macrophage lysates, CPT1a pulled down much less USP50 (Figure xref C, IP Lane 1, xref A), suggesting that mitochondrial STAT3 could contribute to CPT1a stabilization by influencing CPT1a-USP50 binding, at least partially."
34976224