IndraLab

Statements

SMARCA2 binds SMARCA4 and MYSM1. 4 / 4
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sparser
"An interaction of MYSM1 with the BRM and BRG1 components of the SWI/SNF chromatin remodeling complex was also suggested to have a role in the regulation of Ebf1 locus expression [ xref ]."
32344625
sparser
"To confirm the interaction of MYSM1 with BRM or BRG-1, we performed co-immunoprecipitation assays. xref show that MYSM1 was co-precipitated with endogenous BRM and BRG-1 in 293 cells that were transfected with the Flag-MYSM1 expression vector ( xref )."
22169041
sparser
"To further determine the association of MYSM1 and BRM or BRG-1 at the EBF1 promoter locus, sequential two-step ChIP assays were performed. xref shows the association of both MYSM1 and BRM and/or BRG-1 at the Ebf1 promoter locus of WT BM Lin − progenitors."
22169041
sparser
"Collectively, these data demonstrate that MYSM1 interacts with E2A and BRM and/or BRG-1 and its association is likely involved in MYSM1-mediated Ebf1 transcription in B-cell precursors."
22169041