IndraLab

Statements

USP10 binds USP7. 6 / 6
| 3 3
sparser
"Hydroxylation of p53 upon proline 359 regulates its interaction with USP7 and USP10, and its inhibition decreases the association of p53 with USP7/USP10, increases p53 ubiquitination, and rapidly reduces p53 protein levels independently of mRNA expression."
30067985
sparser
"We were able to identify UbVs that bound USP7 or USP10 with high affinity and inhibited deubiquitination activity."
28587923
reach
"The binding of USP7 and USP10 to NHE3 was confirmed by co-immunoprecipitation."
33095475
sparser
"In summary, we have demonstrated that USP7 and USP10 physically interact and ubiquitinate NHE3."
33095475
reach
"We showed that FSK attenuated the interaction of USP7 and USP10 with NHE3, resulting in increased ubiquitination of NHE3."
33095475
reach
"NHE3 is inhibited by protein kinase A. Activation of PKA by forskolin decreased the binding of USP7 and USP10 to NHE3, while increasing ubiquitination of NHE3."
33095475